Panelists discuss the IMscin001 trial findings, which established the noninferiority of subcutaneous atezolizumab with comparable efficacy and safety to the intravenous (IV) formulation.
They highlight operational challenges, including creating multiple electronic medical record (EMR) order sets, standardizing injection times and volumes across products, and addressing nursing workflow considerations during the 2- to 10-minute injection periods.
The subcutaneous formulation of atezolizumab, a PD-L1 inhibitor, received approval approximately 1 year ago based on the IMscin001 phase 3 open-label study findings.
Author's summary: Panel discusses atezolizumab subcutaneous formulation.