Brain Circuit Found to Shape Risk and Impulse Differently by Sex
Researchers exploring risky decision-making in rats found that a specific reward-related neural circuit influences impulsivity and risk-taking in complex ways that depend on timing and biological sex.
Manipulating the circuit during the learning phase of a gambling task altered risky choices differently in males and females, while manipulation after learning affected motor impulsivity in both.
These results reveal that the same brain system can guide distinct behaviors depending on when it’s engaged.
The study suggests that effective treatments for impulsivity-related disorders may need to account for both sex differences and a person’s stage of behavioral learning.
Author summary: Researchers found brain circuit influences impulsivity differently by sex.
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