Biotech Nephrogen combines AI and gene therapy to reverse kidney disease — check it out at TechCrunch Disrupt 2025 | TechCrunch

Biotech Nephrogen: Combining AI and Gene Therapy to Reverse Kidney Disease

Demetri Maxim's motivation to find a cure for kidney disease stems from his personal experience. His mother's kidneys stopped working when he was seven years old, and she had to undergo dialysis four times a week.

Two years later, Maxim's mother received a kidney transplant, but the struggle didn't end there. Maxim inherited Polycystic Kidney Disease (PKD) from his mother, sparking his obsession to find a cure.

About one in seven Americans has Chronic Kidney Disease (CKD), with approximately 10% of those cases due to a genetic condition.

Maxim was convinced that gene therapy could reverse PKD, but the challenge lay in delivering the drugs directly to the diseased cells.

Although Maxim was convinced that gene therapy could reverse PKD, the biggest hurdle was creating a mechanism to deliver the drugs directly to the diseased cells.

Learn more about Biotech Nephrogen's innovative approach at TechCrunch Disrupt 2025.

Author's summary: Biotech Nephrogen uses AI and gene therapy to combat kidney disease.

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TechCrunch TechCrunch — 2025-10-27

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